Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention

October 09, 2026•1 min read

Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention

Gross et al. | Nutrients | 2019

Dr. Elena Gross and colleagues explore how ketone bodies, including D-BHB, may provide an alternative energy source for the brain and act as signaling molecules. The review examines eight areas relevant to migraine: glucose availability, glucose transport, mitochondrial function, oxidative stress, brain excitability, cortical spreading depression, inflammation, and the gut microbiome. Together, these mechanisms provide a scientific foundation for investigating ketones as a nutritional approach to migraine prevention.

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Elena C. Gross, PhD

Elena C. Gross, PhD

Elena C. Gross, PhD, is a neuroscientist and the founder, CEO, and Chief Scientific Officer of KetoSwiss. Her work focuses on brain energy metabolism and nutritional approaches that support how the brain produces and uses energy.

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